{"id":10039,"date":"2026-08-26T00:00:00","date_gmt":"2026-08-25T22:00:00","guid":{"rendered":"https:\/\/www.navarratalent.com\/?p=10035"},"modified":"2026-09-19T03:36:58","modified_gmt":"2026-09-19T01:36:58","slug":"navarra-advances-personalised-cancer-immunotherapy-through-the-pitagoras-project","status":"publish","type":"post","link":"https:\/\/www.navarratalent.com\/en\/navarra-advances-personalised-cancer-immunotherapy-through-the-pitagoras-project\/","title":{"rendered":"Navarra advances personalised cancer immunotherapy through the PIT\u00c1GORAS project"},"content":{"rendered":"<div>\n<div><span lang=\"EN-US\">Navarra<br \/>\ncontinues to make progress in one of the most promising fields of future<br \/>\nmedicine. The <b>PIT\u00c1GORAS project<\/b> has developed a scientific and<br \/>\ntechnological platform focused on personalised cancer immunotherapies, helping<br \/>\nbridge the gap between laboratory research and future clinical applications.<\/span><\/div>\n<div><span lang=\"EN-US\"><br \/><\/span><\/div>\n<div><span lang=\"EN-US\">By<br \/>\ncombining advanced <b>single-cell sequencing technologies with Artificial<br \/>\nIntelligence<\/b>, researchers have successfully identified tumour-specific<br \/>\nT-cell receptors (TCRs). These receptors could be used to design personalised<br \/>\ncellular therapies that are more targeted and potentially offer new<br \/>\npossibilities for patients who currently have limited effective treatment<br \/>\noptions.<\/span><\/div>\n<div><span lang=\"EN-US\"><br \/><\/span><\/div>\n<div><span lang=\"EN-US\">One of the<br \/>\nproject&#8217;s key achievements has been the detailed structural and biophysical<br \/>\ncharacterisation of a particularly promising TCR candidate, together with the<br \/>\ndevelopment of production protocols under <b>GMP clinical standards<\/b>. This<br \/>\nrepresents an important foundation for future clinical trials in humans.<\/span><\/div>\n<div><span lang=\"EN-US\"><br \/><\/span><\/div>\n<div><span lang=\"EN-US\">PIT\u00c1GORAS<br \/>\nalso showcases the strength of Navarra&#8217;s collaborative healthcare and<br \/>\ninnovation ecosystem. The consortium brings together <b>Cima Universidad de<br \/>\nNavarra, Navarrabiomed, Cl\u00ednica Universidad de Navarra, Hospital Universitario<br \/>\nde Navarra, Nasertic, Aditech, 3P Biovian and Neuraraptic AI<\/b>, connecting<br \/>\nscientific research, healthcare, technology and industry.<\/span><\/div>\n<div><span lang=\"EN-US\"><br \/><\/span><\/div>\n<div><span lang=\"EN-US\">The project<br \/>\nreceived <b>\u20ac1.6 million in funding from the Government of Navarra<\/b> through<br \/>\nits 2023-2025 strategic projects programme and the GEMA challenge, focused on<br \/>\npersonalised medicine and advanced therapies.<\/span><\/div>\n<div><span lang=\"EN-US\"><br \/><\/span><\/div>\n<div><span lang=\"EN-US\">The next<br \/>\nstage will involve validating the findings in new patient cohorts, improving AI<br \/>\nalgorithms to increase the precision of tumour-specific TCR identification and<br \/>\nfurther optimising the most promising therapeutic candidates.<\/span><\/div>\n<div><span lang=\"EN-US\"><br \/><\/span><\/div>\n<div><span lang=\"EN-US\">For<br \/>\ninternational professionals, projects like PIT\u00c1GORAS reveal another side of<br \/>\nNavarra: <b>a place where scientific and technological talent can work on<br \/>\ninnovation with real-world impact<\/b>. Biotechnology, AI, biomedical research,<br \/>\nbioinformatics and advanced therapies are creating exciting opportunities for<br \/>\nprofessionals who want to help shape the future of medicine.<\/span><\/div>\n<\/div>\n<div><\/div>\n<div><a href=\"https:\/\/www.navarra.es\/es\/-\/nota-prensa\/el-proyecto-pitagoras-consolida-una-plataforma-cientifica-de-vanguardia-para-el-desarrollo-de-inmunoterapias-personalizadas-contra-el-cancer?pageBackId=363032&amp;back=true\" target=\"_self\">Further information<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p class=\"tx-excerpt\"><div><span lang=\"EN-US\" style=\"font-size:11.0pt;line-height:107%;font-family:&quot;Calibri&quot;,sans-serif\">Science,\r\nartificial intelligence and personalised medicine come together in Navarra. The\r\nPIT\u00c1GORAS project has consolidated a cutting-edge scientific platform designed\r\nto identify tumour-specific targets and move towards more precise, personalised\r\ncancer therapies.<\/span><\/div><\/p>","protected":false},"author":0,"featured_media":10038,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-10039","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sin-categorizar"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Navarra advances personalised cancer immunotherapy through the PIT\u00c1GORAS project - Navarra Talent<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.navarratalent.com\/en\/navarra-advances-personalised-cancer-immunotherapy-through-the-pitagoras-project\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Navarra advances personalised cancer immunotherapy through the PIT\u00c1GORAS project - Navarra Talent\" \/>\n<meta property=\"og:description\" content=\"Science, artificial intelligence and personalised medicine come together in Navarra. 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